Home » PRODUCTS » Bioinformatics »
Celemics Analysis Service
Trust CAS with your Bioinformatics Analysis
Overview
Revolutionary Bioinformatics Solution for your Sequencing Data
Although NGS-based molecular diagnosis technologies have advanced rapidly, existing bioinformatics analysis platforms have not matched the speed of development.
Even as the discovery of various new biomarkers and their applications are becoming more prevalent by the day, there are very few solutions in the market that are able to readily react to client needs. As such, Celemics has developed the Celemics Analysis Service (CAS), a revolutionary bioinformatics solution aiming to provide client-specific services for the current convoluted and restrictive market using real-time client interaction, need-based customized analysis, and the expertise of our bioinformatics analysts.
Features & Benefits
Fast and Accurate Bioinformatics Analysis
CAS allows easy accession of analysis results, even with no prior knowledge of bioinformatics analysis. We can offer suitable analysis methodology based on experimental purpose, conditions, and status. (Germline, somatic, FFPE, cfDNA, RNA, virus, bacteria, non-human, de novo sequencing, methylation sequencing, or more).
Through automated bioinformatics pipeline and bioinformatics experts from Celemics, we provide constant monitoring of all analysis processes and results and also can support real-time troubleshooting and solution provision during analysis process, even for non-standard data sets.
At Celemics, we follow well accepted GATK Best practice pipeline and are GDPR-compliant through usage of Europe-based server.
Accurate Clinical Interpretation: Strand Clinical Report
Sophisticated Client-Customized Data Analysis
The benefit and advantage of using CAS is that we are able to support optimized analysis proposals based on client’s research or clinical purposes.
We propose individualized result data re-processing and visualization based on client needs as well as an annotation option based on additional databases per client request possible (Prior usage confirmation required).
Celemics’ in-house Bioinformaticians also support analysis pipelines other than Celemics’ standard pipelines to be developed based on real-time communication with clients.
Tertiary Analysis - Client-specific Visualization: OncoRisk CNV Analysis
Tertiary Analysis - Client-specific Visualization Curation:
FLT3-ITD Analysis:
visualized by IGV View
Gene Fusion Analysis from FFPE samples
Client Ease of Use
Because we understand the challenges that comes with data analyses in NGS, CAS emphasizes ease of use Bioinformatics solutions.
We reduce initial cost and time for account set-up and user training; instead, we present individual client-based custom analysis possible using a simple data input interface, removing the need for complicated request processes. Team of Celemics’ bioinformatics experts provide real-time real-time troubleshooting and recommendations for your analysis results. Additionally, NGS experts and Celemics continuously monitor the process for issues such as index hopping and will provide alternative solutions.
All results and reports are guaranteed fast data transmission speed and short transmission intervals using servers within the European region.
Secondary Analysis : CAS Visualized Report
Other Features
Cost-effective Service
No base account set-up or user registration fee as expert Bioinformaticians are ready to help with your analysis
Provision of Result with Different Analytic-tiers
highly competitive primary / secondary / tertiary analysis (clinical interpretation included) depending on your needs.
Variants annotated with functional significance and incorporated with AMP Clinical Practice Guidelines
Interoperability with Celemics Target Enrichment Panels
Able to generate analysis results optimized for Celemics panels along with user-friendly Bioinformatics report as per request
Workflow
01. Analysis Request
[Primary Analysis]
FASTQ to annotated VCF
[Secondary Analysis]
CNV, Large InDel, Fusion, TMB & MSI
[Tertiary Analysis]
Clinical Interpretation
[Provision of client]
Requested reports such as BAM/BAI, Annotated VCF, Performance Summary Statistics, Clinical Reports, etc.
Will require prior consultation and agreement.
[Variant Filtration]
Provision of process report for mutation detection using metrics such as VAF, depth, and strand conditions.
[Variant Clinical Significance]
Gathering relevant data types based on clinical information such as mutation type, protein functions, clinical database, etc.
After confirming the analysis request, a Celemics Bl expert will initiate and monitor the analysis
[Data upload]
On-site server or cloud server
[single click, automated upload]
05. Result Guidance
04. Request Interpretaion
03. BI Analysis
02. Data Transmission
Customer
CELEMICS
Customer
Workflow
[Primary Analysis]
FASTQ to annotated VCF
[Secondary Analysis]
CNV, Large InDel, Fusion, TMB & MSI
[Tertiary Analysis]
Clinical Interpretation
[Data upload]
On-site server or cloud server
[single click, automated upload]
After confirming the analysis request, a Celemics Bl expert will initiate and monitor the analysis
[Variant Filtration]
Provision of process report for mutation detection using metrics such as VAF, depth, and strand conditions.
[Variant Clinical Significance]
Gathering relevant data types based on clinical information such as mutation type, protein functions, clinical database, etc.
[Provision of client]
Requested reports such as BAM/BAI, Annotated VCF, Performance Summary Statistics, Clinical Reports, etc.
Will require prior consultation and agreement.
01. Analysis Request
02. Data Transmission
03. BI Analysis
04. Request Interpretaion
05. Result Guidance
Workflow
Related Products
Whole Exome Sequencing
Ultimate exonic coverage; industry-leading capture performance and sequencing efficiency accompanied by complete BI solution
Somatic Cancer
Comprehensive NGS panel for identifying and characterizing the molecular fingerprint for solid tumors with market-leading sensitivity
Liquid Biopsy
Clinically validated ctDNA panel with exceptional accuracy, even for ultra-low VAF variant detection
Library Preparation Kit
Highly optimized, user- convenient NGS library preparation kit for all Celemics panels
Ultimate exonic coverage; industry-leading capture performance and sequencing efficiency accompanied by complete BI solution
Comprehensive NGS panel for identifying and characterizing the molecular fingerprint for solid tumors with market-leading sensitivity
Clinically validated ctDNA panel with exceptional accuracy, even for ultra-low VAF variant detection
Highly optimized, user- convenient NGS library preparation kit for all Celemics panels