Home » 제품 » Ready-to-Use NGS Panel » Somatic Cancer » CancerMaster

CancerMaster Panel

Comprehensive panel for somatic cancer and immuno-oncology markers

Overview
Features & Benefits
Specification
Related Products
Resources
References
Overview
Features & Benefits
Specification
Related Products
Resources
References

Overview

CancerMaster 패널

CancerMaster 패널은 유전자 내 발생하는 모든 유전 변이에 더하여 면역 치료 반응에 중요한 것으로 알려진 마커 (Immuno-oncology 마커)들을 정밀하게 분석할 수 있는 패널입니다. 특히 CNV 분석에서는 암세포 비율에 따라 다른 Cut-off를 적용한 분석을 진행하며 Epstein-Barr Virus (EBV) 및 Human Papillomaviruses (HPV) 분석 또한 진행 가능해 암 연관 유전자들의 종합적인 분석이 가능합니다.

CancerMaster
Features & Benefits

암 연관 유전자에 대한 포괄적인 정보 제공

CancerMaster는 다양한 종류의 암종에 연관된 유전자에 대한 종합적인 분석 결과를 제공하기 위해 개발된 패널입니다. Somatic variants는 물론 TMB, MSI 분석을 위한 Immuno-oncology 마커 및 EBV, HPV와 같은 암 연관 바이러스 분석까지 폭넓은 타겟 범위를 모두 커버할 수 있도록 설계되었습니다

ANALYSIS OF EBV & HPV

EBV (Epstein-Barr Virus)HPV (Human Papillomavirus)
- Related disease - Lymphoma
- Genes - EBV type1 (EBNA-2)		- Related disease - Cervical cancer
- Genes - HPV L1 gene
 (Analysis of a total of 24 types is possible)
Validation for detection of EBV type1 (EBNA - 2)
in control specimens		Analysis of the following 11 types of HPV types was completed using clinical specimens

임상 수준에서 검증된 패널 성능

암 연구는 패널 성능은 통한 일관된 결과를 제공할 수 있어야 함은 물론 재현성이 확보되어야 합니다. 셀레믹스의 CancerMaster 패널은 다양한 표준물질 및 일반적인 샘플은 물론 임상 수준의 검체에 대해서도 성능 평가를 완료한 패널입니다.

Variants of CacerMaster (764 Samples)

Variants of CancerMaster (764 Samples)

Variants of CacerMaster (764 Samples)

Specification

*Gene Add-On Service: Genes can be added by customer’s request.
Gene count*524 genes
Covered regionWhole CDS, Custom regions of oncogenes, immune response genes, and EBV & HPV viruses
Target size2.5 Mb
Mutation typeSNV, Indel, CNV, Rearrangement, TMB, MSI, EBV, HPV
Sample typeFFPE, Fresh frozen tissue (> 50 ng of fragmented DNA)
PlatformAll sequencers from Illumina, Thermo Fisher, MGI, PacBio, and Oxford Nanopore
Bioinformatics Support① Primary Analysis: FASTQ to annotated VCF
② Secondary Analysis: CNV, Large InDel, MSI, TMB
③ Tertiary Analysis: Clinical interpretation

Specification - Gene List

CancerMaster Panel

  • 524 genes | Gene count
  • 2.5 Mb | Target Size
  • Whole CDS, Custom regions of oncogenes, Immune response genes, and EBV & HPV viruses | Target Region
ABL1ABL2ACVR1ACVR1BADAM29ADGRA2AKT1AKT2AKT3ALKALOX12BALOX15BAMER1APCAPCDD1APEX1APOBAPOBEC1APOBEC3
A		APOBEC3
B
ARARAFARFRP1ARID1AARID1BARID2ASXL1ATMATP11BATRATRXAURKAAURKBAXIN1AXLB2MB3GAT1BACH1BAP1BARD1
BCL2BCL2A1BCL2L1BCL2L2BCL6BCL9BCORBCORL1BCRBIRC2BIRC3BLMBRAFBRCA1BRCA2BRD2BRD3BRD4BRIP1BTG1
BTKBTLACARD11CASP5CASP8CBFBCBLCCDC150CCDC168CCDC43CCL2CCL4CCND1CCND2CCND3CCNE1CD27CD274CD276CD28
CD3DCD3ECD3GCD4CD40CD44CD79ACD79BCD8ACDC42CDC73CDH1CDH2CDH20CDH5CDK12CDK4CDK6CDK8CDKN1A
CDKN1BCDKN2ACDKN2BCDKN2CCDX2CEBPACHD1CHD2CHD4CHEK1CHEK2CHUKCICCRBNCREBBPCRKLCRLF2CSF1RCSF2CSF2RA
CSF2RBCSNK2A1CTCFCTLA4CTNNA1CTNNB1CUL3CUL4ACUL4BCXCL10CXCL11CXCL9CXCR3CYLDCYP17A1DAXXDCUN1D1DDR2DICER1DIS3
DNMT1DNMT3ADOCK2DOT1LEGFRELMO1EML4EMSYEP300EPHA3EPHA5EPHA6EPHA7EPHB1EPHB4EPHB6ERBB2ERBB3ERBB4ERCC1
ERCC2ERGERRFI1ESR1ETV1ETV4ETV5ETV6EWSR1EYA2EZH2FAM46CFANCAFANCCFANCD2FANCEFANCFFANCGFANCIFANCL
FANCMFASFAT1FAT3FBXW7FGF1FGF10FGF12FGF14FGF19FGF2FGF23FGF3FGF4FGF6FGF7FGFR1FGFR2FGFR3FGFR4
FHFLCNFLT1FLT3FLT4FOXA1FOXL2FOXO3FOXP1FOXP3FRS2FUBP1GABRA6GAS6GATA1GATA2GATA3GATA4GATA6GID4
GLI1GNA11GNA13GNAQGNASGRIN2AGRM3GSK3BGUCY1A2GZMAGZMBGZMHH3F3AHGFHIST1H3BHLA-AHLA-BHLA-CHLA-DRAHLA-E
HLA-FHLA-GHNF1AHOXA3HRASHSD3B1HSP90AA1IDH1IDH2IDO1IDO2IFITM1IFITM3IFNA1IFNB1IFNGIGF1IGF1RIGF2IGF2R
IKBKEIKZF1IL12AIL12BIL2IL23AIL6IL7RINHBAINPP4BINSRIRF2IRF4IRS2ITGAEITKJAK1JAK2JAK3JUN
KAT6AKDM5AKDM5CKDM6AKDRKEAP1KELKITKLF4KLHL6KMT2AKMT2BKMT2CKNSTRNKRASLAG3LMO1LRP1BLRP6LTK
LYNLZTR1MAGI2MAGOHMAML1MAP2K1MAP2K2MAP2K4MAP3K1MAP3K13MAPK1MAXMCL1MDM2MDM4MED12MEF2BMEN1METMITF
MLH1MPLMRE11MSH2MSH6MTORMUTYHMYBMYCMYCLMYCNMYD88MYO18ANCOA3NCOR1NF1NF2NFE2L2NFKBIANKX2-1
NKX2-8NKX3-1NOTCH1NOTCH2NOTCH3NOTCH4NPM1NRASNSD1NSD3NTRK1NTRK2NTRK3NUP93NUTM1PAK3PAK5PALB2PARK2PARP1
PARP2PARP3PARP4PAX5PBRM1PDCD1PDCD1LG2PDGFRAPDGFRBPDK1PGRPHF6PHLPP2PIK3C2BPIK3C3PIK3CAPIK3CBPIK3CGPIK3R1PIK3R2
PKHD1PLCG1PLCG2PMS2PNPPNRC1POLD1POLEPPARGPPP2R1APRDM1PREX2PRF1PRKAR1APRKCIPRKDCPRPF40BPRSS8PTCH1PTCH2
PTENPTK2PTPN11PTPRCPTPRDQKIRAB35RAC1RAC2RAD17RAD50RAD51RAD51BRAD51CRAD51DRAD52RAD54LRAF1RANBP2RARA
RB1RBM10RELRETRHEBRHOARHOBRICTORRNF43ROBO1ROBO2ROS1RPA1RPS6KB1RPTORRUNX1RUNX1T1RUNX3SDHASDHB
SDHCSDHDSEMA3ASEMA3ESETSETBP1SETD2SF3A1SF3B1SH2B3SKP2SLIT2SMAD2SMAD3SMAD4SMARCA1SMARCA4SMARCB1SMARCD1SMO
SNCAIPSOCS1SOX10SOX2SOX9SPENSPOPSPTA1SRCSRSF1SRSF2SRSF7STAG2STAT3STAT4STK11SUFUSYKTACC3TAF1
TBX22TBX3TERCTERTTET2TGFBR2TIAF1TIGITTIPARPTMPRSS2TNFTNFAIP3TNFRSF14TNFRSF18TNFRSF4TNFSF13BTNKSTNKS2TOP1TOP2A
TP53TRAF7TRRAPTSC1TSC2TSHRU2AF1U2AF2USP9XVEGFAVHLVSIRVTCN1WISP3WNT1WT1WWP1XBP1XPO1XRCC3
ZBTB2ZNF217ZNF703ZRSR2

Related Products

Ready-to-use-panel

CancerMaster

암종과 연관 있는 것으로 알려진 유전자의 염기서열을 포괄적으로 분석하기 위한 패널. Immuno-oncology 마커를 비롯해 Gene Rearrangement 등 다양한 유전 변이를 분석하기 위한 패널

View Detail >
Ready-to-use-panel

OncoRisk

유전성 암과 연관 있는 것으로 보고된 30여 개 유전자의 염기서열 분석을 위한 패널

View Detail >
Ready-to-use-panel

CancerScreen Focus

FDA 승인된 약물과 연관있는 것으로 알려진 유전변이 검출을 위한 패널로 약물과 연관성이 높은 주요 유전자를 폭넓게 커버하는 패널

View Detail >
Celemics Analysis Service

CAS

셀레믹스에서 제공하는 BI 분석 서비스로 다양한 수준의 분석 결과 제공 가능

View Detail >

Resources

Technical Resources

[Product Overview] CancerMaster Panel

Download

[Product Overview] Celemics Target Enrichment Panel Overview

Download

[Catalogue] Celemics Products & Service Catalogue_All Products & Service

Download

Safety Data Sheets

최신 MSDS 파일이 필요하시면 ‘Contact Us‘를 통해 문의 주시기 바랍니다.

MSDS_CancerMaster Panel_Illumina

MSDS_CancerMaster Panel_Thermo Fisher

MSDS_CancerMaster Panel_MGI

References

Germline BRCA testing in routine clinical practice: a single-center experience

Pathology & Oncology Research

Germline BRCA testing in routine clinical practice: a single-center experience

Nikolényi, A., Dobi, Á., Sántha, D., Kószó, R., Iványi, M., Horváth, E., … & Kahán, Z. (2026). Germline BRCA testing in routine clinical practice: a single-center experience. Pathology and Oncology Research, 32, 1612238.

 

10.3389/pore.2026.1612238


View Detail >

Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology

Scientific Reports

Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology

Che, J., Kwon, W. S., Kim, J., Jadamba, E., Han, H. J., Kim, Y., … & Rha, S. Y. (2026). Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology. Scientific Reports.

 

10.1038/s41598-026-37991-0


View Detail >

Germline and somatic mutational variants of Tunisian high grade serous ovarian cancer identified by next-generation sequencing

BMC Cancer

Germline and somatic mutational variants of Tunisian high grade serous ovarian cancer identified by next-generation sequencing

Ammous-Boukhris, N., Abdelmaksoud-Dammak, R., Ben Kridis, W., Ben-Ayed-Guerfali, D., Shtaiwi Abed, A., Guidara, S., … & Mokdad-Gargouri, R. (2025). Germline and somatic mutational variants of Tunisian high grade serous ovarian cancer identified by next-generation sequencing. BMC cancer, 25(1), 1542.

 

10.1186/s12885-025-14989-x


View Detail >

Genetic profiling of inherited colorectal cancer syndromes in Tunisian patients

PloS One

Genetic profiling of inherited colorectal cancer syndromes in Tunisian patients

Abdelmaksoud-Dammak, R., Ammous-Boukhris, N., Saadallah-Kallel, A., Ayed-Guerfali, D. B., Guidara, S., Miladi-Abdennadher, I., … & Mokdad-Gargouri, R. (2025). Genetic profiling of inherited colorectal cancer syndromes in Tunisian patients. Plos one, 20(6), e0326343.

 

10.1371/journal.pone.0326343


View Detail >