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PharmacoScreen Panel
Flexible choice targeting over 120 genes associated with Pharmacogenomics
Available with prescribed drugs of the corresponding diseases
The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >Hybridization-based target enrichment panel with our intrinsic probe design, rebalancing, and molecular barcode technologies to efficiently analyze not only hard-to-capture areas but also challenging samples, such as damaged DNA or RNA.
View Detail >End-to-end customized target enrichment panel with assay optimization, validation and even complete BI support. Over 1,000 custom panels developed world-wide. White-labeled customized product for business expansion also available.
View Detail >Revolutionary Bioinformatics solution providing fast and
accurate, client-specific analysis services.
Trust CAS with your BI analysis !
Celemics offers easy-to-use kit with all components needed from RNA fragmentation to double-stranded cDNA synthesis suitable for NGS.
View Detail >Celemics exclusive enzymes and buffers for enhanced hybridization to ensure improved coverage and uniformity.
View Detail >Proven market-leading purification and size selection efficiency supported by Celemics’ unique magnetic bead-based chemistry. Compatible with all Celemics’ panels as well as other NGS providers
View Detail >High-quality streptavidin bead that selectively isolates biotinylated ligands bound to hybridization probes; minimizing DNA loss during the target enrichment process.
View Detail >CeleNM™ Bead streamlines library quantification and normalization in Next-Generation Sequencing (NGS). Say goodbye to traditional QC processes, saving time and costs while ensuring robust results. Experience uniform sequencing data distribution and comparable on-target ratios with CeleNM™ Bead.
View Detail >Celemics’ highly optimized polymerase ensures market-leading amplification efficiency and accuracy with minimized PCR bias and error rate.
View Detail >Highly optimized library preparation kit to be used with all Celemics ready-to-use or customized panels. Experience the incomparable efficiency and performance for NGS library preparation
View Detail >The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >Celemics’ comprehensive NGS panel for somatic cancer allows highly accurate and comprehensive analysis for identifying significant mutations and variants for solid tumors.
Celemics’ comprehensive NGS panel for somatic cancer allows highly accurate and comprehensive analysis for identifying significant mutations and variants for solid tumors.
Celemics has developed NGS ctDNA-based kits for colon, breast, and lung cancer assays. We have integrated our market-leading proprietary technologies and thoroughly validated and optimized as ready-to-use panels for clinical diagnostics.
Celemics offers end-to-end NGS-based detection and discovery solutions for Biopharma, CRO, and Drug discovery research fields.
In order to overcome the limitations of analyzing clinical diseases with conventional whole exome sequencing, Celemics introduces NGS-based clinical diagnostic solution for efficient detection of disease-causing variants for inherited diseases.
Celemics offers flexible choice of assessing extensive target regions associated with Pharmacogenomics for client-specific drug prescription and drug metabolism.
Celemics’ virus panels are designed to detect and identify disease-causing viruses. With our exclusive technologies, we provide efficient and accurate detection of targeted virus trains as well as procurement of credible data for whole viral genome sequencing.
To fulfill the expectations and growing needs for sequencing animals and plants, Celemics offers range of ready-to-use applicable to agrigenomics field as well as an option for developing customized NGS panel to specifically fit individual research purposes.
With Celemics’ proprietary technologies for assay development and optimization, we offer complete and robust NGS solutions for transcriptome, fusion, and isoform analyses for various sample types and conditions.
Celemics provides comprehensive solution for DNA methylation sequencing with proprietary probes specifically designed for methyl-seq, enabling accurate detection of methylation sites.
Complete solution with flexible panel design for characterization and differentiation of a myriad of microbial species.
Accurate and efficient analysis of IGH population that can detect MRD as low as 10-6 with optimized primers that can minimize sequencing loss and PCR duplications.
Celemics introduces revolutionary BI solution aiming to provide client-specific service. We provide fast, accurate, and sophisticated analyses of your NGS data accompanied by our proprietary bioinformatics pipeline.
The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >End-to-end customized target enrichment panel with assay optimization, validation and even complete BI support. Over 1,000 custom panels developed world-wide. White-labeled customized product for business expansion also available.
View Detail >Utilizing NGS-based target enrichment methods for higher genotyping efficiency and accuracy. Providing cost-effective and optimized experiment compared to conventional methods, such as GBS, PCR and microarray in plant and animal research
View Detail >
Revolutionary Bioinformatics solution providing fast and
accurate, client-specific analysis services.
Trust CAS with your BI analysis
Providing NGS-based diagnostics solutions for biopharma companies. Celemics can develop and deliver a flexible customization and commercialization services while maintaining the market-leading performance for our clients interested in clinical and companion diagnostics.
View Detail >Tailored-fit customized assay development from designing to validation run; including not only the custom panel design but also species-specific or sequencer-specific blockers, followed by reagent conditioning to optimize the individual experiment and sequencer.
View Detail >The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >Find useful information, insights and tools for your Celemics’ products and services
View Detail >Explore the most up-to-date publications featuring Celemics’ products and services
View Detail >Sharing interesting stories about the world of NGS and how Celemics delivers the innovative NGS solutions to the world of science.
View Detail >Explore a diverse range of engaging video content, from fascinating experiments showcasing cutting-edge research to heartfelt customer testimonials.
View Detail >Find useful information, insights and tools for your Celemics’ products and services
View Detail >In-silico designed and wet-lab validated exclusive probes to ensure state-of-the-art capture performance
View Detail >Stay up-to-date with the latest updates on our activities, events and achievements
View Detail >Let’s change the NGS market together – our global presence and partners world-wide
View Detail >Waiting for your experience with Celemics, an innovative leader in NGS industry
View Detail >Flexible choice targeting over 120 genes associated with Pharmacogenomics
Available with prescribed drugs of the corresponding diseases
PharmacoScreen 패널은 약물대사에 연관 있는 것으로 알려진 유전자 분석을 위해 만들어진 패널입니다. 치료를 목적으로 한 약물 처방 시의 효과성 등을 연구할 때 유용한 패널입니다.
PharmacoScreen 패널은 Standard, Epilepsy, Anti-tuberculosis의 세 가지 타입의 패널이 있습니다.
1. Standard
PharmacoScreen Standard 패널은 장기 이식과 연관 있는 것으로 알려진 유전자들을 대상으로 만들어진 패널로 약물 대사, Transporters, 파킨슨씨 병 연관 유전자 등이 포함되어 있습니다.
2. Epilepsy
PharmacoScreen Epilepsy 패널은 뇌전증 약물 반응에 대한 연구를 위해 개발된 패널로, 관련 약물 처방이 필요한지를 평가할 때 유용하게 사용될 수 있습니다.
3. Anti-tuberculosis
PharmacoScreen Anti-tuberculosis 패널의 주요 타겟은 약물 유발 간 손상입니다. 약물이 유발하는 간 손상은 약물 개발에 있어 중요한 평가 요소 중의 하나로 이에 대한 연구에 본 패널이 유용하게 사용될 수 있습니다.
PharmacoScreen은 4개 대학병원과의 협업으로 개발된 패널로 약물동태학, 약력학과 관계된 120여 개 유전자로 구성되어 있습니다. 실제 임상 샘플로 테스트 완료한 패널을 공급합니다.
PharmacoScreen Standard, Epilepsy, Anti-tuberculosis 패널들은 각각 122, 91, 132개 유전자를 포함하고 있습니다. 하지만 여타 다른 셀레믹스 패널들과 같이 Gene Add-on 서비스를 통해 원하는 유전자를 추가하여 보다 유용하게 사용할 수 있습니다.
Standard | Epilepsy | Anti-tuberculosis | |
---|---|---|---|
Gene count* | 283 genes | 91 genes | 132 genes |
Covered region | Whole CDS + UTR (-50 bp, +10 bp) | ||
Target size | 634 kb | 575 kb | 186 kb |
Mutation type | SNV, Indel, CNV | ||
Sample type (amount) | Blood (> 50 ng of fragmented DNA) | ||
Platform | All sequencers from Illumina, Thermo Fisher, MGI, and PacBio | ||
Bioinformatics pipeline | Primary, Secondary and Tertiary analysis result (FASTQ to VCF, VCF to Clinical report) |
Pharmaco Screen Panel Standard |
ABCA1 | ABCB1 | ABCB11 | ABCB4 | ABCB7 | ABCC1 | ABCC2 | ABCC3 | ABCC4 | ABCC5 | ABCC6 | ABCC8 | ABCC9 | ABCG1 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABCG2 | ABP1 | ACE | ADH1A | ADH1B | ADH1C | ADH4 | ADH5 | ADH6 | ADH7 | ADRB1 | ADRB2 | AHR | AKAP9 | |
ALB | ALDH1A1 | ALDH2 | ALDH3A1 | ALDH3A2 | ALOX5 | AOX1 | APOA1 | APOA2 | ARID5B | ARNT | ARSA | ATP7A | ATP7B | |
BDNF | BRCA1 | CA5P | CACNA1C | CBR1 | CBR3 | CDA | CES1 | CES2 | CFTR | CHST1 | CHST10 | CHST11 | CHST13 | |
CHST2 | CHST3 | CHST4 | CHST5 | CHST6 | CHST7 | CHST8 | CHST9 | COMT | CPS1 | CRHR1 | CROT | CYP11A1 | CYP11B1 | |
CYP11B2 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1A2 | CYP1B1 | CYP20A1 | CYP21A2 | CYP24A1 | CYP26A1 | CYP26C1 | CYP27A1 | CYP27B1 | CYP2A13 | |
CYP2A6 | CYP2A7 | CYP2B6 | CYP2B7P1 | CYP2C18 | CYP2C19 | CYP2C8 | CYP2C9 | CYP2D6 | CYP2E1 | CYP2F1 | CYP2J2 | CYP2R1 | CYP2S1 | |
CYP39A1 | CYP3A4 | CYP3A43 | CYP3A5 | CYP3A7 | CYP46A1 | CYP4A11 | CYP4B1 | CYP4F11 | CYP4F12 | CYP4F2 | CYP4F3 | CYP4F8 | CYP4Z1 | |
CYP51A1 | CYP7A1 | CYP7B1 | CYP8B1 | DBH | DCK | DPYD | DRD1 | DRD2 | EGFR | EPHX1 | EPHX2 | ESR1 | F5 | |
FAAH | FKBP5 | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | FMO6 | G6PD | GLCCI1 | GRK4 | GRK5 | GSTA1 | GSTA2 | |
GSTA3 | GSTA4 | GSTA5 | GSTM1 | GSTM2 | GSTM3 | GSTM4 | GSTM5 | GSTO1 | GSTP1 | GSTT1 | GSTT2 | GSTZ1 | HMGCR | |
HNMT | HTR1A | HTR2A | KCNH2 | KCNJ11 | LDLR | MAOA | MAOB | MAT1A | METTL1 | MTHFR | NAT1 | NAT2 | NNMT | |
NQO1 | NR1I2 | NR1I3 | NR3C1 | NR3C2 | NTRK2 | ORM1 | ORM2 | P2RY1 | P2RY12 | PEAR1 | PGAP3 | PNMT | PON1 | |
PON2 | PON3 | POR | PPARD | PPARG | PPP1R9A | PRSS53 | PTGIS | PTGS1 | PTGS2 | QPRT | RALBP1 | RPL13 | RXRA | |
RYR1 | RYR2 | SCN1A | SCN2A | SCN5A | SERPINA7 | SETD4 | SLC10A1 | SLC10A2 | SLC13A1 | SLC15A1 | SLC15A2 | SLC16A1 | SLC19A1 | |
SLC22A1 | SLC22A11 | SLC22A12 | SLC22A13 | SLC22A14 | SLC22A2 | SLC22A3 | SLC22A4 | SLC22A5 | SLC22A6 | SLC22A7 | SLC22A8 | SLC25A27 | SLC28A1 | |
SLC28A2 | SLC28A3 | SLC29A1 | SLC29A2 | SLC47A1 | SLC47A2 | SLC5A6 | SLC6A3 | SLC6A4 | SLC6A6 | SLC7A5 | SLC7A7 | SLC7A8 | SLCO1A2 | |
SLCO1B1 | SLCO1B3 | SLCO2B1 | SLCO3A1 | SLCO4A1 | SLCO5A1 | SOD2 | SPG7 | SPN | SULT1A1 | SULT1A2 | SULT1A3 | SULT1B1 | SULT1C2 | |
SULT1C4 | SULT1E1 | SULT2A1 | SULT2B1 | SULT4A1 | TBXAS1 | TPMT | TPSG1 | TYMS | UGT1A | UGT1A1 | UGT1A10 | UGT1A3 | UGT1A4 | |
UGT1A5 | UGT1A6 | UGT1A7 | UGT1A8 | UGT1A9 | UGT2A1 | UGT2B11 | UGT2B15 | UGT2B17 | UGT2B28 | UGT2B4 | UGT2B7 | UGT8 | VDR | |
VKORC1 | XDH | ZNF423 |
Pharmaco Screen Panel Epilepsy |
ANKK1 | CACNA1A | CACNA1B | CACNA1D | CACNA1E | CACNA1F | CACNA1G | CACNA1H | CACNA1I | CACNA1S | CACNA2D1 | CACNA2D2 | CACNA2D3 | CACNA2D4 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CACNB1 | CACNB2 | CACNB3 | CACNB4 | CACNG1 | CACNG2 | CACNG3 | CACNG4 | CACNG5 | CACNG6 | CACNG7 | CACNG8 | CDH13 | CLCN2 | |
EFHC1 | GABRA1 | GABRA2 | GABRA3 | GABRA4 | GABRA5 | GABRA6 | GABRB1 | GABRB2 | GABRB3 | GABRD | GABRE | GABRG1 | GABRG2 | |
GABRG3 | GABRP | GABRQ | GABRR1 | GABRR2 | GABRR3 | GRIA1 | GRIA2 | GRIA3 | GRIA4 | GRIK1 | GRIK2 | GRIK3 | GRIK4 | |
GRIK5 | GRIN1 | GRIN2A | GRIN2B | GRIN2C | GRIN2D | GRIN3A | GRIN3B | HNF4A | HTR1B | KCNA2 | KCNB1 | KCNC1 | KCND3 | |
KCNH1 | KCNJ10 | KCNQ2 | KCNQ3 | KCNT1 | KCTD7 | LEPR | MAOA | MAOB | RBFOX1 | SCN1A | SCN2A | SCN3A | SCN8A | |
STS | TPH1 | TPH2 | UGT1A10 | UGT1A6 | UGT1A7 | UGT1A9 |
Pharmaco Screen Panel Anti- Tuberculosis |
ABHD5 | ADA | ADORA2A | ALAS1 | ALPK2 | ANO10 | ASAH1 | BACH1 | BAX | BCL2 | BTLA | CARD8 | CASP1 | CASP3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CASP8 | CASP9 | CAT | CCL2 | CD274 | CD276 | CD28 | CD40 | CD40LG | CD80 | CD86 | CPA6 | CTLA4 | CYBA | |
DDX10 | DPP4 | ENTPD1 | FAHD2A | FAS | FASLG | FBXW8 | FOXP3 | GCLC | GCLM | GGT1 | GPX1 | GPX3 | GPX4 | |
GSR | GSS | GSTA1 | GSTA2 | GSTA3 | GSTA4 | GSTA5 | GSTK1 | GSTM2 | GSTM3 | GSTM4 | GSTM5 | GSTO1 | GSTO2 | |
GSTT2 | GSTZ1 | HAVCR2 | HIF1A | HMOX1 | HMOX2 | HSPA1L | ICOS | ICOSLG | IDO1 | IDO2 | IFNG | IFNGR1 | IFNGR2 | |
IL10 | IL10RA | IL12A | IL12B | IL12RB1 | IL12RB2 | IL17A | IL17RA | IL18 | IL18R1 | IL18RAP | IL1A | IL1B | IL1R1 | |
IL4 | IL4R | IL6 | IL6R | KCNE3 | KCNIP3 | KEAP1 | KSR2 | LAG3 | LGALS9 | MAFK | MIR4272 | MPO | NFE2L2 | |
NLRP3 | NOS1 | NOS2 | NOS3 | NT5E | PDCD1 | PDCD1LG2 | PLXNA4 | POLD3 | PROM2 | PSD3 | SOD1 | SOD3 | SRXN1 | |
STAT3 | TGFB1 | TGFBR1 | THSD7B | TNFRSF4 | TNF | TNFAIP3 | TNFRSF14 | TNFRSF1A | TNFRSF1B | TNFRSF9 | TNFSF10 | TNFSF14 | TNFSF4 | |
TNFSF9 | TRIM43 | TXNRD1 | USP44 | VTCN1 | ZNF804B |
NGS Library Preparation 키트로 셀레믹스의 Target Enrichment 패널에 최적화된 키트
셀레믹스에서 제공하는 BI 분석 서비스로 다양한 수준의 분석 결과 제공 가능
최고 품질의 마그네틱 비드로 사용하기 편리하며 높은 재현성을 보여 NGS 실험에 최적화된 비드
PCR 반응에 필요한 모든 구성요소를 포함하고 있는 믹스 제품이며 NGS에서 요구하는 정확도를 충족한 제품
Technical Resources
[Product Sheet] PharmacoScreen Panel
[Product Overview] Celemics Target Enrichment Panel Overview
[Catalogue] Celemics Products & Service Catalogue_All Products & Service
Safety Data Sheets
MSDS_PharmacoScreen Panel_Illumina_Enzymeplus
MSDS_PharmacoScreen Panel_Illumina
MSDS_PharmacoScreen Panel_Thermo Fisher
MSDS_PharmacoScreen Panel_MGI_EnzymePlus
MSDS_PharmacoScreen Panel_MGI