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High-throughput Genotyping
NGS-based target enrichment methods for higher genotyping efficiency in plant and animal research
The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >Hybridization-based target enrichment panel with our intrinsic probe design, rebalancing, and molecular barcode technologies to efficiently analyze not only hard-to-capture areas but also challenging samples, such as damaged DNA or RNA.
View Detail >End-to-end customized target enrichment panel with assay optimization, validation and even complete BI support. Over 1,000 custom panels developed world-wide. White-labeled customized product for business expansion also available.
View Detail >Revolutionary Bioinformatics solution providing fast and
accurate, client-specific analysis services.
Trust CAS with your BI analysis !
Celemics offers easy-to-use kit with all components needed from RNA fragmentation to double-stranded cDNA synthesis suitable for NGS.
View Detail >Celemics exclusive enzymes and buffers for enhanced hybridization to ensure improved coverage and uniformity.
View Detail >Proven market-leading purification and size selection efficiency supported by Celemics’ unique magnetic bead-based chemistry. Compatible with all Celemics’ panels as well as other NGS providers
View Detail >High-quality streptavidin bead that selectively isolates biotinylated ligands bound to hybridization probes; minimizing DNA loss during the target enrichment process.
View Detail >CeleNM™ Bead streamlines library quantification and normalization in Next-Generation Sequencing (NGS). Say goodbye to traditional QC processes, saving time and costs while ensuring robust results. Experience uniform sequencing data distribution and comparable on-target ratios with CeleNM™ Bead.
View Detail >Celemics’ highly optimized polymerase ensures market-leading amplification efficiency and accuracy with minimized PCR bias and error rate.
View Detail >Highly optimized library preparation kit to be used with all Celemics ready-to-use or customized panels. Experience the incomparable efficiency and performance for NGS library preparation
View Detail >The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >Celemics’ comprehensive NGS panel for somatic cancer allows highly accurate and comprehensive analysis for identifying significant mutations and variants for solid tumors.
Celemics’ comprehensive NGS panel for somatic cancer allows highly accurate and comprehensive analysis for identifying significant mutations and variants for solid tumors.
Celemics has developed NGS ctDNA-based kits for colon, breast, and lung cancer assays. We have integrated our market-leading proprietary technologies and thoroughly validated and optimized as ready-to-use panels for clinical diagnostics.
Celemics offers end-to-end NGS-based detection and discovery solutions for Biopharma, CRO, and Drug discovery research fields.
In order to overcome the limitations of analyzing clinical diseases with conventional whole exome sequencing, Celemics introduces NGS-based clinical diagnostic solution for efficient detection of disease-causing variants for inherited diseases.
Celemics offers flexible choice of assessing extensive target regions associated with Pharmacogenomics for client-specific drug prescription and drug metabolism.
Celemics’ virus panels are designed to detect and identify disease-causing viruses. With our exclusive technologies, we provide efficient and accurate detection of targeted virus trains as well as procurement of credible data for whole viral genome sequencing.
To fulfill the expectations and growing needs for sequencing animals and plants, Celemics offers range of ready-to-use applicable to agrigenomics field as well as an option for developing customized NGS panel to specifically fit individual research purposes.
With Celemics’ proprietary technologies for assay development and optimization, we offer complete and robust NGS solutions for transcriptome, fusion, and isoform analyses for various sample types and conditions.
Celemics provides comprehensive solution for DNA methylation sequencing with proprietary probes specifically designed for methyl-seq, enabling accurate detection of methylation sites.
Complete solution with flexible panel design for characterization and differentiation of a myriad of microbial species.
Accurate and efficient analysis of IGH population that can detect MRD as low as 10-6 with optimized primers that can minimize sequencing loss and PCR duplications.
Celemics introduces revolutionary BI solution aiming to provide client-specific service. We provide fast, accurate, and sophisticated analyses of your NGS data accompanied by our proprietary bioinformatics pipeline.
The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >End-to-end customized target enrichment panel with assay optimization, validation and even complete BI support. Over 1,000 custom panels developed world-wide. White-labeled customized product for business expansion also available.
View Detail >Utilizing NGS-based target enrichment methods for higher genotyping efficiency and accuracy. Providing cost-effective and optimized experiment compared to conventional methods, such as GBS, PCR and microarray in plant and animal research
View Detail >
Revolutionary Bioinformatics solution providing fast and
accurate, client-specific analysis services.
Trust CAS with your BI analysis
Providing NGS-based diagnostics solutions for biopharma companies. Celemics can develop and deliver a flexible customization and commercialization services while maintaining the market-leading performance for our clients interested in clinical and companion diagnostics.
View Detail >Tailored-fit customized assay development from designing to validation run; including not only the custom panel design but also species-specific or sequencer-specific blockers, followed by reagent conditioning to optimize the individual experiment and sequencer.
View Detail >The most comprehensive whole exome panel that covers the target regions of all major WES panels in the market. With our proprietary technologies, we provide industry-leading performance and efficiency with complete BI solution.
View Detail >Find useful information, insights and tools for your Celemics’ products and services
View Detail >Explore the most up-to-date publications featuring Celemics’ products and services
View Detail >Sharing interesting stories about the world of NGS and how Celemics delivers the innovative NGS solutions to the world of science.
View Detail >Explore a diverse range of engaging video content, from fascinating experiments showcasing cutting-edge research to heartfelt customer testimonials.
View Detail >Find useful information, insights and tools for your Celemics’ products and services
View Detail >In-silico designed and wet-lab validated exclusive probes to ensure state-of-the-art capture performance
View Detail >Stay up-to-date with the latest updates on our activities, events and achievements
View Detail >Let’s change the NGS market together – our global presence and partners world-wide
View Detail >Waiting for your experience with Celemics, an innovative leader in NGS industry
View Detail >NGS-based target enrichment methods for higher genotyping efficiency in plant and animal research
시퀀싱 기술의 발전으로 인간 유전체에 대해서는 분자 마커, 전체 유전체 서열 및 전사체 정보와 같은 다양한 자원이 제공되었으나, 농업 유전체학에 필요한 정보들은 아직 부족하며 또한 접근하기 쉽지 않은 상태입니다. 셀레믹스의 High-throughput Genotyping 패널은 Hybridization 기반 캡처 기술을 활용하여 타겟 유전자 영역을 고도로 농축시켜 비용 효율적으로 필요한 정보를 얻습니다. 이렇게 얻은 정보는 분자 육종 분야 등 유전체 정보가 필요한 농업 유전체학 연구에 새로운 통찰력을 제공합니다.
NGS 기반의 Target Enrichment 방법은 기존의 GBS, PCR 및 Microarray에 비해 높은 정확도 및 비용 효율적으로 실험할 수 있습니다.
새로운 SNV 마커의 발굴을 비롯해 100에서 10,000개의 마커에 대한 포괄적인 검사를 수행합니다. False-negative 및 False-positives 등 판정의 오류를 최소화한 높은 정확도를 가진 패널을 공급합니다.
연구하고자 하는 종에 맞춰 최적화된 Blocking Reagent를 사용합니다. 보다 효율적으로 맞춤 제작된 패널을 제공하므로 비용 효율적인 연구를 수행할 수 있습니다.
셀레믹스에서는 High-throughput 패널의 데이터 분석을 위해 특별히 고안된 Library Preparation 키트, 타겟 캡처 기술 및 인덱스를 공급합니다. 이를 통해 높은 효율로 대량의 유전자 정보를 처리할 수 있습니다.
Advantages | Disadvantage | |
---|---|---|
Conventional GBS | 1. Sequencing of multiple samples due to lower amount of data required compared to WGS | 1. Limited biomarkers available due to limited conserved regions, reducing overall resolution 2. Unable to detect SNPs in the restriction sites |
Microarray |
1. Higher reproducibility than conventional
GBS |
1. Hard to customize new targets (novel biomarkers) 2. Low flexibility to meet various kinds of genotyping |
PCR | 1. Cost-effective for low number of samples 2. Easy and fast analysis | 1. Limited number of biomarkers to analyze at once 2. Inappropriate for mass-analysis of biomarkers |
Celemics Target Enrichment | 1. Cost saving : Highly cost-effective when assessing multiple samples
2. Flexible customization : Novel biomarkers can be added or removed 3. Comprehensive analysis : Including novel SNP discovery 4. Exceptional performance : Celemics proprietary blocking oligo design technology 5. Wide compatibility : Compatible with a wide range of sample types |
고객의 목적에 맞게 유전자 영역을 자유롭게 구성한 NGS 패널로 시약부터 프로토콜까지 최적화된 패널 제공
NGS Library Preparation 키트로 셀레믹스의 Target Enrichment 패널에 최적화된 키트
셀레믹스에서 제공하는 BI 분석 서비스로 다양한 수준의 분석 결과 제공 가능
최고 품질의 마그네틱 비드로 사용하기 편리하며 높은 재현성을 보여 NGS 실험에 최적화된 비드
Hwang J, Bang S, Choi MH, Hong SH, Kim SW, Lee HE, Yang JH, Park US, Choi YJ. Discovery and Validation of Survival-Specific Genes in Papillary Renal Cell Carcinoma Using a Customized Next-Generation Sequencing Gene Panel. Cancers. 2024 Jan;16(11):2006.
10.3390/cancers16112006
Ammous-Boukhris N, Abdelmaksoud-Dammak R, Ben Ayed-Guerfali D, Guidara S, Jallouli O, Kamoun H, Charfi Triki C, Mokdad-Gargouri R. Case report: Compound heterozygous variants detected by next-generation sequencing in a Tunisian child with ataxia-telangiectasia. Frontiers in Neurology. 2024 May 31;15:1344018.
10.3389/fneur.2024.1344018
Hwang J, Lee HE, Han JS, Choi MH, Hong SH, Kim SW, Yang JH, Park U, Jung ES, Choi YJ. Sex-specific survival gene mutations are discovered as clinical predictors of clear cell renal cell carcinoma. Scientific Reports. 2024 Jul 9;14(1):15800.
10.1038/s41598-024-66525-9