㈜셀레믹스

Probe Design Technology

In-silico designed and wet-lab validated to ensure state-of-the-art capture performance

Probe Design Technology

  • Post category:Technology

About

독자적인 프로브 디자인 기술

셀레믹스에서는 디자인된 모든 프로브에 대해 실제 실험을 하여 성능을 평가합니다. 많은 회사들이 In silico 방법만으로 프로브의 캡처 수준과 친화력을 예측하고 있으나 실제 실험 결과와는 많이 다릅니다. 따라서 프로브의 성능을 정확히 알기 위해서는 디자인된 후에 실제 실험을 통해 캡처 성능을 확인해야 합니다.

셀레믹스는 디자인된 프로브의 성능을 보장하기 위해 다음과 같은 과정을 거칩니다.

빅데이터 기반 프로브 디자인 프로세스를 활용하여 타겟 영역에 대한 최적의 프로브 조합을 선택합니다. 그 후 표준물질을 통해 실제 실험을 통해 프로브 성능 검증을 수행하고 ‘Rebalancing’을 통해 Coverage와 Uniformity를 보정합니다.

Market Problem and Celemics' Answer

Probe Design Technology

Proprietary Probe Design Algorithm

Based on extensive wet-lab target capture experimentation for every customized panel

Resources

Technical Resources

[Product Sheet] Whole Exome Sequencing Panel

[Product Overview] Celemics Target Enrichment Panel Overview

[Catalogue] Celemics Products & Service Catalogue_All Products & Service

Safety Data Sheets

MSDS_Whole Exome Sequencing Panel_Illumina

MSDS_Whole Exome Sequencing Panel_MGI

MSDS_Whole Exome Sequencing Panel_Thermo Fisher

References

Genes

Development and Application of a Target Capture Sequencing SNP-Genotyping Platform in Rice

Lee C, Cheon KS, Shin Y, Oh H, Jeong YM, Jang H, et al. Development and Application of a Target Capture Sequencing SNP-Genotyping Platform in Rice. Genes (Basel). 2022 Apr 28;13(5):794.

 

DOI 10.3390/genes13050794


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BIODIVERSITAS

Genetic diversity and phylogenetic analysis of Khiew-Phalee chickens based on mitochondrial DNA cytochrome b gene sequences

Phromnoi S, Lertwatcharasarakul P, Phattanakunanan S. Genetic diversity and phylogenetic analysis of Khiew-Phalee chickens based on mitochondrial DNA cytochrome b gene sequences. Biodiversitas Journal of Biological Diversity [Internet]. 2022 Jan 30 [cited 2023 Feb 20];23(2). Available from: https://smujo.id/biodiv/article/view/10153

 

DOI 10.13057/biodiv/d230220


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Veterinary World

First report on molecular characteristics and risk factor analysis of Ehrlichia canis in dogs in Khon Kaen, Thailand

Mitpasa T, Sarker BR, Macotpet A, Bupata PA, Sangmaneedet S, Taweenan W. First report on molecular characteristics and risk factor analysis of Ehrlichia canis in dogs in Khon Kaen, Thailand. Vet World. 2022 Jan;15(1):232–8.

 

DOI 10.14202/vetworld.2022.232-238


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Genes

Using Transcriptome Analysis to Explore Gray Mold Resistance-Related Genes in Onion (Allium cepa L.)

Lee HM, Park JS, Kim SJ, Kim SG, Park YD. Using Transcriptome Analysis to Explore Gray Mold Resistance-Related Genes in Onion (Alliumcepa L.). Genes (Basel). 2022 Mar 18;13(3):542.

 

DOI 10.3390/genes13030542


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