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분자 바코드를 통해 정확한 Consensus read 생성 및 매우 낮은 빈도의 유전변이 발굴 가능

셀레믹스 독자적인 분자 바코드는 NGS Library Preparation 과정을 보다 특별하게 만들어줍니다. Duplication Read를 효과적으로 제거할 수 있으며 보다 정확한 Consensus Read를 생성할 수 있습니다. 이를 통해 기존의 Duplication Read 제거 방법에 비해 더 많은 수의 Unique Read를 확보해 분석 정확도를 높일 수 있습니다.

분자 바코드 도입을 통해 PCR 및 시퀀싱에서 발생한 오류 제거 및 시퀀싱 잡음을 최소화할 수 있어 시퀀싱 효율을 극대화할 수 있습니다. 특히, False-positive를 줄이고 특히 매우 낮은 VAF에 대한 감지 민감도가 필요한 분야의 연구 효율을 극대화할 수 있습니다.

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Molecular Barcode

Resources

Technical Resources

[Product Sheet] Whole Exome Sequencing Panel

[Product Overview] Celemics Target Enrichment Panel Overview

[Catalogue] Celemics Products & Service Catalogue_All Products & Service

Safety Data Sheets

MSDS_Whole Exome Sequencing Panel_Illumina

MSDS_Whole Exome Sequencing Panel_MGI

MSDS_Whole Exome Sequencing Panel_Thermo Fisher

References

Genes

Development and Application of a Target Capture Sequencing SNP-Genotyping Platform in Rice

Lee C, Cheon KS, Shin Y, Oh H, Jeong YM, Jang H, et al. Development and Application of a Target Capture Sequencing SNP-Genotyping Platform in Rice. Genes (Basel). 2022 Apr 28;13(5):794.

 

DOI 10.3390/genes13050794


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BIODIVERSITAS

Genetic diversity and phylogenetic analysis of Khiew-Phalee chickens based on mitochondrial DNA cytochrome b gene sequences

Phromnoi S, Lertwatcharasarakul P, Phattanakunanan S. Genetic diversity and phylogenetic analysis of Khiew-Phalee chickens based on mitochondrial DNA cytochrome b gene sequences. Biodiversitas Journal of Biological Diversity [Internet]. 2022 Jan 30 [cited 2023 Feb 20];23(2). Available from: https://smujo.id/biodiv/article/view/10153

 

DOI 10.13057/biodiv/d230220


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Veterinary World

First report on molecular characteristics and risk factor analysis of Ehrlichia canis in dogs in Khon Kaen, Thailand

Mitpasa T, Sarker BR, Macotpet A, Bupata PA, Sangmaneedet S, Taweenan W. First report on molecular characteristics and risk factor analysis of Ehrlichia canis in dogs in Khon Kaen, Thailand. Vet World. 2022 Jan;15(1):232–8.

 

DOI 10.14202/vetworld.2022.232-238


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Genes

Using Transcriptome Analysis to Explore Gray Mold Resistance-Related Genes in Onion (Allium cepa L.)

Lee HM, Park JS, Kim SJ, Kim SG, Park YD. Using Transcriptome Analysis to Explore Gray Mold Resistance-Related Genes in Onion (Alliumcepa L.). Genes (Basel). 2022 Mar 18;13(3):542.

 

DOI 10.3390/genes13030542


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