• Just like a chameleon utilizing its
    colored pigments and crystals to
    adapt to its surroundings,
    we proactively pioneer and adapt to
    the everchanging NGS markets with
    our cutting-edge technology to
    support our customer’s needs.

Innovation in NGS based material

Celemics’ Publications

Science is a collaborative process which works best when new knowledge is shared. We contribute to this by presenting our research
at scientific congresses and publishing our results in scientific journals.

2022 (2)
Jan. 31. 2022

First report on molecular characteristics and risk factor analysis of Ehrlichia canis in dogs in Khon Kaen, Thailand

- Vet World. doi:10.14202/vetworld.2022.232-238 

Learn more
Jan. 21. 2022

SARS-CoV-2 in hospital air as revealed by comprehensive respiratory viral panel sequencing

Environment and Life Sciences Research Center, Kuwait Institute for Scientific Research, Kuwait 

Learn more
2021 (17)
Oct. 06. 2021

First report on molecular prevalence and identification of Anaplasma platys in dogs in Khon Kaen, Thailand

- Vet World. 2021 Oct;14(10):2613-2619. doi: 10.14202/vetworld.2021.2613-2619. Epub 2021 Oct 6

doi: 10.14202/vetworld.2021.2613-2619

Learn more
Jul. 20. 2021

Prevalence of cancer susceptibility variants in patients with multiple Lynch syndrome related cancers

Sci Rep. 2021 Jul 20;11(1):14807. doi: 10.1038/s41598-021-94292-4.

Learn more
Jun. 02. 2021

Functional Characteristics of Novel FGFR1 Mutations in Patients with Isolated Gonadotropin-Releasing Hormone Deficiency

Exp Clin Endocrinol Diabetes. 2021 Jun;129(6):457-463. doi: 10.1055/a-1151-4800. Epub 2020 Jun 2. 

Learn more
May. 21. 2021

Clinical and Genetic Characteristics of Korean Congenital Stationary Night Blindness Patients

Genes (Basel). 2021 May 21;12(6):789. doi: 10.3390/genes12060789. 

Learn more
May. 13. 2021

The Combination of Single-Cell and Next-Generation Sequencing Can Reveal Mosaicism for BRCA2 Mutations and the Fine Molecular Details of Tumorigenesis

Cancers (Basel). 2021 May 13;13(10):2354. doi: 10.3390/cancers13102354. 

Learn more
May. 06. 2021

Genetic Confirmation and Identification of Novel Variants for Glanzmann Thrombasthenia and Other Inherited Platelet Function Disorders: A Study by the Korean Pediatric Hematology Oncology Group (KPHOG)

Genes (Basel). 2021 May 6;12(5):693. doi: 10.3390/genes12050693. 

Learn more
May. 01. 2021

Metaphyseal Dysplasia Without Hypotrichosis Caused by RNA Component of Mitochondrial RNA-Processing Endoribonuclease (RMRP) Gene Variants: The First Case in Korea

Ann Lab Med. 2021 May 1;41(3):346-349. doi: 10.3343/alm.2021.41.3.346. 

Learn more
May. 01. 2021

A Case of Acute Myeloid Leukemia With inv(16)(p13.1q22);CBFB-MYH11 Presenting With Faggot Cells

Ann Lab Med. 2021 May 1;41(3):333-335. doi: 10.3343/alm.2021.41.3.333. 

Learn more
Apr. 21. 2021

Molecular Characterization of Biliary Tract Cancer Predicts Chemotherapy and PD‐1/PD‐L1 Blockade Responses

Hepatology. 2021 Apr 21. doi: 10.1002/hep.31862. 

Learn more
Feb. 01. 2021

Targeted next-generation sequencing-based detection of microsatellite instability in colorectal carcinomas

PLoS One. 2021 Feb 1;16(2): e0246356. doi: 10.1371/journal.pone.0246356 

Learn more
Jan. 31. 2021

Neutralization of Zika virus by E protein domain III-Specific human monoclonal antibody

Biochem Biophys Res Commun. 2021 Mar 19;545:33-39. doi: 10.1016/j.bbrc.2021.01.075. Epub 2021 Jan 31. 

Learn more
Jan. 20. 2021

Genomic mutation profiling using liquid biopsy in Korean patients with prostate cancer: Circulating tumor DNA mutation predicts the development of castration resistance

Investig Clin Urol. 2021 Mar;62(2):224-232. doi: 10.4111/icu.20200406. 

Learn more
Jan. 15. 2021

An Overview of Characteristics of Clinical Next-Generation Sequencing–Based Testing for Hematologic Malignancies

Arch Pathol Lab Med. 2021 Jan 15. doi: 10.5858/arpa.2019-0661-CP. 

Learn more
Jan. 07. 2021

Genome Sequences of Two GH Clade SARS-CoV-2 Strains Isolated from Patients with COVID-19 in South Korea

Microbiol Resour Announc. 2021 Jan 7;10(1):e01384-20. doi: 10.1128/MRA.01384-20. 

Learn more
Jan. 01. 2021

Genetic Evaluation of Congenital Hypothyroidism with Gland in situ Using Targeted Exome Sequencing

Ann Clin Lab Sci. 2021 Jan;51(1):73-81. 

Learn more
Jan. 01. 2021

Genomic profiling of extracellular vesicle-derived DNA from bronchoalveolar lavage fluid of patients with lung adenocarcinoma

Transl Lung Cancer Res. 2021 Jan;10(1):104-116. doi: 10.21037/tlcr-20-888. 

Learn more
Jan. 01. 2021

Development of the phenylpyrazolo [3, 4-d] pyrimidine-based, insulin-like growth factor receptor/Src/AXL-targeting small molecule kinase inhibitor

Theranostics. 2021 Jan 1;11(4):1918-1936. doi: 10.7150/thno.48865. eCollection 2021. 

Learn more
2020 (17)
Dec. 31. 2020

Ultradeep Sequencing Analysis of Paroxysmal Nocturnal Hemoglobinuria Clones Detected by Flow Cytometry: PIG Mutation in Small PNH Clones

Am J Clin Pathol. 2021 Jun 17;156(1):72-85. doi: 10.1093/ajcp/aqaa211. 

Learn more
Nov. 30. 2020

Evidence of Long-Distance Droplet Transmission of SARS-CoV-2 by Direct Air Flow in a Restaurant in Korea

J Korean Med Sci. 2020 Nov 30;35(46):e415. doi: 10.3346/jkms.2020.35.e415. 

Learn more
Oct. 07. 2020

Development and validation of a next-generation sequencing-based multigene assay to predict the prognosis of estrogen receptor-positive, HER2-negative breast cancer

Clin Cancer Res. 2020 Dec 15;26(24):6513-6522. doi: 10.1158/1078-0432.CCR-20-2107. Epub 2020 Oct 7. 

Learn more
Sep. 26. 2020

Molecular Characteristics of Sequence Variants in GATA4 in Patients with 46, XY Disorders of Sex Development without Cardiac Defects

Sex Dev. 2019;13(5-6):240-245. doi: 10.1159/000511258. Epub 2020 Sep 26. 

Learn more
Sep. 19. 2020

Phenotype-based single cell sequencing identifies diverse genetic subclones in CD133 positive cancer stem cells

Biochem Biophys Res Commun. 2021 Jun 18;558:209-215. doi: 10.1016/j.bbrc.2020.09.005. Epub 2020 Sep 19. 

Learn more
Aug. 10. 2020

Detailed analysis of phenotypes and genotypes in megalencephaly-capillary malformation-polymicrogyria syndrome caused by somatic mosaicism of PIK3CA mutations

Orphanet J Rare Dis. 2020 Aug 10;15(1):205. doi: 10.1186/s13023-020-01480-y. 

Learn more
Aug. 07. 2020

Genetic heterogeneity and prognostic impact of recurrent ANK2 and TP53 mutations in mantle cell lymphoma: a multi-centre cohort study

Sci Rep. 2020 Aug 7;10(1):13359. doi: 10.1038/s41598-020-70310-9. 

Learn more
Aug. 06. 2020

Exon splicing analysis of intronic variants in multigene cancer panel testing for hereditary breast/ovarian cancer

Cancer Sci. 2020 Oct;111(10):3912-3925. doi: 10.1111/cas.14600. Epub 2020 Sep 2.

Learn more
Aug. 01. 2020

Molecular Diagnosis of Craniosynostosis Using Targeted Next-Generation Sequencing

Neurosurgery. 2020 Aug 1;87(2):294-302. doi: 10.1093/neuros/nyz470.

Learn more
Jul. 29. 2020

Incidental Severe Fatty Degeneration of the Erector Spinae in a Patient with L5–S1 Disc Extrusion Diagnosed with Limb-Girdle Muscular Dystrophy R2 Dysferin-Related

Diagnostics (Basel). 2020 Jul 29;10(8):530. doi: 10.3390/diagnostics10080530. 

Learn more
Jul. 06. 2020

Anaplastic Thyroid Cancer Arising from Dyshormonogenetic Goiter: c.3070T>C and Novel c.7070T>C Mutation in the Thyroglobulin Gene

Thyroid. 2020 Nov;30(11):1676-1680. doi: 10.1089/thy.2020.0248. Epub 2020 Jul 6.

Learn more
May. 07. 2020

Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing

PLoS One. 2020 May 7;15(5):e0232754. doi: 10.1371/journal.pone.0232754. eCollection 2020. 

Learn more
May. 04. 2020

Differential contributions of sarcomere and mitochondria-related multigene variants to the endophenotype of hypertrophic cardiomyopathy

Mitochondrion. 2020 Jul;53:48-56. doi: 10.1016/j.mito.2020.04.010. Epub 2020 May 4. 

Learn more
Apr. 02. 2020

Single-cell analysis of a mutant library generated using CRISPR-guided deaminase in human melanoma cells

Commun Biol. 2020 Apr 2;3(1):154. doi: 10.1038/s42003-020-0888-2.

Learn more
Mar. 29. 2020

A High-Throughput Single-Clone Phage Fluorescence Microwell Immunoassay and Laser-Driven Clonal Retrieval System

Biomolecules. 2020 Mar 29;10(4):517. doi: 10.3390/biom10040517.

Learn more
Feb. 04. 2020

Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test

Cancer Res Treat. 2020 Jul;52(3):697-713. doi: 10.4143/crt.2019.559. Epub 2020 Feb 4. 

Learn more
Jan. 14. 2020

Spontaneous mutations in the single TTN gene represent high tumor mutation burden

NPJ Genom Med. 2020 Jan 14;5:33. doi: 10.1038/s41525-019-0107-6. eCollection 2020.

Learn more
2019 (13)
Oct. 17. 2019

Implementation of a Targeted Next-Generation Sequencing Panel for Constitutional Newborn Screening in High-Risk Neonates

Yonsei Med J. 2019 Nov;60(11):1061-1066. doi: 10.3349/ymj.2019.60.11.1061. 

Learn more
Jul. 23. 2019

Telomere length and its correlation with gene mutations in chronic lymphocytic leukemia in a Korean population

PLoS One. 2019 Jul 23;14(7):e0220177. doi: 10.1371/journal.pone.0220177. eCollection 2019. 

Learn more
Jul. 12. 2019

Targeted sequencing aids in identifying clonality in chronic myelomonocytic leukemia

Leuk Res. 2019 Sep;84:106190. doi: 10.1016/j.leukres.2019.106190. Epub 2019 Jul 12. 

Learn more
Jul. 03. 2019

Next-generation sequencing with comprehensive bioinformatics analysis facilitates somatic mosaic APC gene mutation detection in patients with familial adenomatous polyposis

BMC Med Genomics. 2019 Jul 3;12(1):103. doi: 10.1186/s12920-019-0553-0. 

Learn more
Jun. 26. 2019

Somatic mosaic truncating mutations of PPM1D in blood can result from expansion of a mutant clone under selective pressure of chemotherapy

PLoS One. 2019 Jun 26;14(6):e0217521. doi: 10.1371/journal.pone.0217521. eCollection 2019. 

Learn more
Jun. 17. 2019

Clinical utility of targeted NGS panel with comprehensive bioinformatics analysis for patients with acute lymphoblastic leukemia

Leuk Lymphoma. 2019 Dec;60(13):3138-3145. doi: 10.1080/10428194.2019.1627538. Epub 2019 Jun 17. 

Learn more
May. 10. 2019

FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm

Ann Lab Med. 2019 May;39(3):327-329. doi: 10.3343/alm.2019.39.3.327. 

Learn more
May. 07. 2019

Impact of next‐generation sequencing panels in the evaluation of limb‐girdle muscular dystrophies

Ann Hum Genet. 2019 Sep;83(5):331-347. doi: 10.1111/ahg.12319. Epub 2019 May 7. 

Learn more
Apr. 13. 2019

Cytogenetic evolution in myeloproliferative neoplasms with different molecular abnormalities

Blood Cells Mol Dis. 2019 Jul;77:120-128. doi: 10.1016/j.bcmd.2019.04.007. Epub 2019 Apr 13. 

Learn more
Mar. 21. 2019

p53 expression status is associated with cancer-specific survival in stage III and high-risk stage II colorectal cancer patients treated with oxaliplatin-based adjuvant chemotherapy

Br J Cancer. 2019 Apr;120(8):797-805. doi: 10.1038/s41416-019-0429-2. Epub 2019 Mar 21.

Learn more
Mar. 06. 2019

Targeted next generation sequencing can serve as an alternative to conventional tests in myeloid neoplasms

PLoS One. 2019 Mar 6;14(3):e0212228. doi: 10.1371/journal.pone.0212228. eCollection 2019. 

Learn more
Mar. 04. 2019

Enzymatic construction of shRNA library from oligonucleotide library

Genes Genomics. 2019 May;41(5):573-581. doi: 10.1007/s13258-019-00800-2. Epub 2019 Mar 4. 

Learn more
Feb. 12. 2019

High-throughput retrieval of physical DNA for NGS-identifiable clones in phage display library

MAbs. 2019 Apr;11(3):532-545. doi: 10.1080/19420862.2019.1571878. Epub 2019 Feb 12.

Learn more
2018 (10)
Oct. 17. 2018

Comparison of Clinical Features and Outcomes in Epithelial Ovarian Cancer according to Tumorigenicity in Patient-Derived Xenograft Models

Cancer Res Treat. 2018 Jul;50(3):956-963. doi: 10.4143/crt.2017.181. Epub 2017 Oct 17. 

Learn more
Oct. 10. 2018

ASXL1 is a molecular predictor in idiopathic cytopenia of undetermined significance

Leuk Lymphoma. 2019 Mar;60(3):756-763. doi: 10.1080/10428194.2018.1492129. Epub 2018 Oct 10. 

Learn more
Oct. 02. 2018

Urinary Exosomal and cell-free DNA Detects Somatic Mutation and Copy Number Alteration in Urothelial Carcinoma of Bladder

Sci Rep. 2018 Oct 2;8(1):14707. doi: 10.1038/s41598-018-32900-6. 

Learn more
Sep. 27. 2018

Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility

Cancers (Basel). 2018 Sep 27;10(10):361. doi: 10.3390/cancers10100361.

Learn more
Sep. 14. 2018

Targeted Gene Panel Sequencing for Molecular Diagnosis of Kallmann Syndrome and Normosmic Idiopathic Hypogonadotropic Hypogonadism

Exp Clin Endocrinol Diabetes. 2019 Sep;127(8):538-544. doi: 10.1055/a-0681-6608. Epub 2018 Sep 14. 

Learn more
Aug. 24. 2018

Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites

Sci Rep. 2018 Aug 24;8(1):12724. doi: 10.1038/s41598-018-31097-y. 

Learn more
May. 01. 2018

Pyrosequencing-based quantitative measurement of CALR mutation allele burdens and their clinical implications in patients with myeloproliferative neoplasms

Clin Chim Acta. 2018 Aug;483:183-191. doi: 10.1016/j.cca.2018.05.001. Epub 2018 May 1. 

Learn more
Mar. 15. 2018

Frequency of hereditary neuropathy with liability to pressure palsies (HNPP) due to 17p11.2 deletion in a Korean newborn population

Orphanet J Rare Dis. 2018 Mar 15;13(1):40. doi: 10.1186/s13023-018-0779-5. 

Learn more
Jan. 29. 2018

Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Nat Biotechnol. 2018 Mar;36(3):239-241. doi: 10.1038/nbt.4061. Epub 2018 Jan 29.

Learn more
Jan. 16. 2018

Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer

BMC Cancer. 2018 Jan 16;18(1):83. doi: 10.1186/s12885-017-3940-y. 

Learn more
2017 (7)
Dec. 19. 2017

Optimization of RNA Extraction from Formalin-Fixed Paraffin-Embedded Blocks for Targeted Next-Generation Sequencing

J Breast Cancer. 2017 Dec;20(4):393-399. doi: 10.4048/jbc.2017.20.4.393. Epub 2017 Dec 19. 

Learn more
Nov. 29. 2017

Variants of Lipolysis-Related Genes in Korean Patients with Very High Triglycerides

Yonsei Med J. 2018 Jan;59(1):148-153. doi: 10.3349/ymj.2018.59.1.148. 

Learn more
Oct. 31. 2017

Idiopathic hypereosinophilia is clonal disorder? Clonality identified by targeted sequencing

PLoS One. 2017 Oct 31;12(10):e0185602. doi: 10.1371/journal.pone.0185602. eCollection 2017. 

Learn more
Oct. 16. 2017

Rare and common variants of APOB and PCSK9 in Korean patients with extremely low low-density lipoprotein-cholesterol levels

PLoS One. 2017 Oct 16;12(10):e0186446. doi: 10.1371/journal.pone.0186446. eCollection 2017. 

Learn more
Sep. 27. 2017

Detection of Germline Mutations in Patients with Epithelial Ovarian Cancer Using Multi-gene Panels: Beyond BRCA1/2

Cancer Res Treat. 2018 Jul;50(3):917-925. doi: 10.4143/crt.2017.220. Epub 2017 Sep 27. 

Learn more
Jul. 12. 2017

Telomere length and somatic mutations in correlation with response to immunosuppressive treatment in aplastic anaemia

Br J Haematol. 2017 Aug;178(4):603-615. doi: 10.1111/bjh.14691. Epub 2017 Jul 12.

Learn more
May. 02. 2017

Asymmetrical barcode adapter-assisted recovery of duplicate reads and error correction strategy to detect rare mutations in circulating tumor DNA

Sci Rep. 2017 May 2;7:46678. doi: 10.1038/srep46678. 

Learn more
2016 (4)
Dec. 13. 2016

Genomic Profile of Chronic Lymphocytic Leukemia in Korea Identified by Targeted Sequencing

PLoS One. 2016 Dec 13;11(12):e0167641. doi: 10.1371/journal.pone.0167641. eCollection 2016 

Learn more
Aug. 24. 2016

A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD

Gut. 2017 Nov;66(11):1926-1935. doi: 10.1136/gutjnl-2016-311921. Epub 2016 Aug 24. 

Learn more
Aug. 11. 2016

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer

Oncotarget. 2016 Sep 27;7(39):63252-63260. doi: 10.18632/oncotarget.11207. 

Learn more
Jul. 28. 2016

Short telomere length and its correlation with gene mutations in myelodysplastic syndrome

J Hematol Oncol. 2016 Jul 28;9(1):62. doi: 10.1186/s13045-016-0287-9. 

Learn more
2015 (5)
Sep. 05. 2015

Clinical features of familial hypercholesterolemia in Korea: Predictors of pathogenic mutations and coronary artery disease–A study supported by the Korean Society of Lipidology and Atherosclerosis

Atherosclerosis. 2015 Nov;243(1):53-8. doi: 10.1016/j.atherosclerosis.2015.08.033. Epub 2015 Sep 5. 

Learn more
Apr. 18. 2015

Cytogenetic heterogeneity and their serial dynamic changes during acquisition of cytogenetic aberrations in cultured mesenchymal stem cells

Mutat Res. 2015 Jul;777:60-8. doi: 10.1016/j.mrfmmm.2015.04.003. Epub 2015 Apr 18. 

Learn more
Mar. 16. 2015

Targeted next-generation sequencing for the genetic diagnosis of dysferlinopathy

Neuromuscul Disord. 2015 Jun;25(6):502-10. doi: 10.1016/j.nmd.2015.03.006. Epub 2015 Mar 16. 

Learn more
Feb. 27. 2015

Skeletal overgrowth syndrome caused by overexpression of C-type natriuretic peptide in a girl with balanced chromosomal translocation, t(1;2)(q41;q37.1)

Am J Med Genet A. 2015 May;167A(5):1033-8. doi: 10.1002/ajmg.a.36884. Epub 2015 Feb 27. 

Learn more
Feb. 26. 2015

Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing

BMC Cancer. 2015 Feb 26;15:85. doi: 10.1186/s12885-015-1077-4. 

Learn more